Neue Schritt für Schritt Karte Für Erhaltungstherapie mit Methadontabletten
Neue Schritt für Schritt Karte Für Erhaltungstherapie mit Methadontabletten
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Methadone clearance may Beryllium increased during pregnancy. Several small studies have demonstrated significantly lower trough methadone plasma concentrations and shorter methadone half-lives in women during their pregnancy compared to after their delivery.
The initial methadone dose should Beryllium carefully titrated to the individual. Too rapid titration for the patient's sensitivity is more likely to produce adverse effects.
Methadone hydrochloride tablets can cause physical dependence. Do not stop taking methadone hydrochloride tablets or any other opioid without first talking to your doctor. You could become sick with uncomfortable withdrawal symptoms because your body has become used to these medicines.
Methadone can be abused rein a manner similar to other opioid agonists, legal or illicit. This should be considered when prescribing or dispensing methadone hydrochloride tablets hinein situations where the clinician is concerned about an increased risk of misuse, abuse, or diversion.
The total daily dose, potency and specific characteristics of the opioid the patient had been taking previously, if any;
Since methadone is lipophilic, it has been known to persist in the liver and other tissues. The slow release from the liver and other tissues may prolong the duration of methadone action despite low plasma concentrations.
Abnormal fetal nonstress tests (NSTs) have been reported to occur more frequently when the test is performed 1 to 2 hours after a maintenance dose of methadone in late pregnancy compared to controls.
Pediatric – The pharmacokinetics of methadone have not been evaluated rein the pediatric Tierbestand.
Opioid antagonists should not Beryllium administered hinein the absence of clinically significant respiratory or cardiovascular depression. Hinein an individual physically dependent on opioids, the administration of the usual dose of an opioid antagonist may precipitate an acute withdrawal syndrome.
Patients should be cautioned that methadone, like all opioids, may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving or operating machinery.
The intensity Methadontabletten ohne Rezept online of the syndrome does not always correlate with the maternal dose or the duration of maternal exposure. The duration of the withdrawal signs may vary from a few days to weeks or even months. There is no consensus on the appropriate management of infant withdrawal.
Die erforderlichen Kontrolluntersuchungen des weiteren die mindestens einmal jährliche Blutabnahme sind auf jeden Sache sehr empfehlenswert außerdem sollten weiterhin hinein Anforderung genommen werden.
Do not drink alcohol while using methadone hydrochloride tablets. It may increase the chance of having dangerous side effects.
For people with liver problems: If you have liver problems or a history of liver disease, you may not Beryllium able to process this drug well. This may increase the levels of methadone hinein your body and cause more side effects. Your doctor should watch you closely if you take this drug.